How to Make Your Botox Last Longer
- Nicola Lowrey
- Mar 21
- 2 min read
Botox is a wonder drug that never ceases to amaze me! As my patients know, Botox treatment results will typically be seen in about 3-5 days. Full onset of effect is achieved at 2 weeks, and duration of effect is approximately 3-4 months.

But what if there was a way to prolong our Botox results? At N2 Aesthetics, we pride ourselves on delivering the highest quality of evidence-based, anatomically focused education. Aesthetic medicine is just that – medicine. Like any other specialty, we stick to the science. No snake oil here!
Here are my three tips to maximize the duration of your Botox treatment:
1. Take daily Zinc supplements: In a double-blind, placebo-controlled study published in the Journal of Drugs in Dermatology, 92% of study participants who supplemented their diet with 50 mg of daily zinc intake experienced approximately 30% increase in the duration of their Botox treatment. Ready more about the study here.

2. Try combining a corrective chemical peel with same-day neurotoxin treatment: Patients who underwent a VI Peel followed by a same-day Botox treatment reported a 60% improvement in the severity of their wrinkles. The photographic evidence of before and after images at day 7 and day 30 were truly impressive. Furthermore, 100% of study participants agreed that their skin looked better after the combination of VI Peel and Botox – as opposed to solely their usual quarterly Botox treatment. The images don’t lie! Check them out here.
3. Dose yourself appropriately: Let’s be honest. Dosing = duration! Avoid “baby Botox” and opt for the appropriate therapeutic dose of Botox well suited for longevity. Under-dosing multiple areas on the face may result in the Botox only lasting 1-2 months. Failing to wait a full 90-days between treatments can cause you to become resistant to the neurotoxin, negating its effects. Trust your provider to create a customized treatment plan that is suited to your individual anatomy, as well as the size and strength of your facial muscles.
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